Awesome! This question has already 1 answers..
Hello Milan, glad you like CreateProxy!
Back to your question, If you press Delete Proxies button, than CreateProxy will automatically remove all instances in selected profile (it will remove all instances in your AWS console and also remove all related proxies and instances in CreateProxy).
Just one tip: If you want you can create more profiles for single provider, this way you can remove just some instances and keep alive others (based on profile).